Taurine, A Natural LXRalpha, May Promote Amyloid Beta Clearance in the Brain

There is very recent evidence that the nutrient taurine can activate an intracellular receptor known as LXRalpha. Certain drugs capable of activating this receptor – not yet available clinically – are beneficial in rodent models of Alzheimer’s disease, largely because they promote degradation of toxic amyloid beta protein complexes by brain microglial cells. It is proposed that high-dose supplementation with non-toxic taurine may have similar protective potential.

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