Memo: Carvedilol for Blood Pressure Control in Metabolic Syndrome and Type 2 Diabetes

“Metabolic syndrome” – typically associated with increased abdominal fat, elevated levels of triglycerides and insulin, low HDL cholesterol, and raised blood pressure – is a key cause of vascular disease, diabetes, and cancer. This syndrome is usually associated with increased activity of the sympathetic nervous system – often manifesting as high resting heart rate and blood pressure – and such an increase appears to increase risk for vascular disorders, cancer, and total mortality. The drug carvedilol, often used to treat hypertension and heart failure, may provide notable protection to people with metabolic syndrome by blocking the effects of excessive sympathetic activity.

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