How can you know that CC diets will increase healthspan?

Most important is the literature on caloric restriction and intermittent fasting. But the clinical experience of the Hellers is that overweight people tend to get a lot leaner on CC diets, and metabolic parameters associated with metabolic syndrome (blood pressure, triglycerides, HDL) as well as LDL tend to improve markedly. All of these changes point to decidedly lower risk for diabetes, heart disease, and cancer — and these are some of the key disorders that decrease healthspan.

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