Monthly Archives: January 2011

How can I estimate my degree of caloric restriction — as understood in Caloric Restriction Experiments — from my measurement of the reduction in caloric consumption that I am experiencing?

By estimating your average daily calorie intake at baseline, and then once again after your weight has equilibrated after a year or so of CC dieting, you can calculate the percent reduction in daily calorie intake made possible by your … More scientific detail

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I’ve lost a lot of weight with carb concentrated dieting, and now that my weight has equilibrated, I calculate that my daily calorie intake is lower than that of my “reference man” with a BMI of 22 — but my own BMI is still higher than that. In other words, I’m achieving true calorie restriction, but I’m not as lean as I would expect to be. What’s the problem?

Studies show that, when people lose a lot of weight, their daily energy expenditure tends to decline.   In fact, when their weight equilibrates, their daily energy expenditure tends to be lower than that of people of comparable size and body … More scientific detail

Posted in Caloric Restriction and Intermittent Fasting, FAQs | Comments Off on I’ve lost a lot of weight with carb concentrated dieting, and now that my weight has equilibrated, I calculate that my daily calorie intake is lower than that of my “reference man” with a BMI of 22 — but my own BMI is still higher than that. In other words, I’m achieving true calorie restriction, but I’m not as lean as I would expect to be. What’s the problem?

Mice experiments on caloric restriction compare caloric restricted mice with mice eating as they wish (ad libitum). By contrast, in human dieting, humans eat less calories than they were doing previously at their higher weight. How can the reduction in calories of the human, e.g. a reduction of 20%, be compared and calibrated with the forced reduction of the mice? What role does the reference-man calculation comparing caloric consumption with a same-BMI person of BMI 22 mean here?

Here is no truly objective way to calculate the degree of calorie restriction you are achieving on a CC diet regimen or other calorie restriction protocols. Obviously, you can calculate your percent reduction of calorie intake from baseline when you … More scientific detail

Posted in Caloric Restriction and Intermittent Fasting, FAQs | Comments Off on Mice experiments on caloric restriction compare caloric restricted mice with mice eating as they wish (ad libitum). By contrast, in human dieting, humans eat less calories than they were doing previously at their higher weight. How can the reduction in calories of the human, e.g. a reduction of 20%, be compared and calibrated with the forced reduction of the mice? What role does the reference-man calculation comparing caloric consumption with a same-BMI person of BMI 22 mean here?

What role does autophagy play in improving the health of cells outside the nervous system and what do we know about its role with regard to the brain?

Studies show that stimulation of autophagy is plays a vital role in the life prolongation achieved by calorie restriction in lower organisms such as yeast and worms. Many scientists suspect that a key mediator of the health benefits of prolonged … More scientific detail

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What can I take with a carb-rich meal that could decrease the post-meal elevations in both glucose and insulin?

A more uniformly beneficial strategy that CC dieters can use to minimize the effective glycemic index of carb-rich meals is to include factors such as soluble fiber, vinegar, or almonds. These have the potential to suppress meal-induced increases in both … More scientific detail

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Does combining my carbohydrates with protein or fat dilute the glycemic index of the carbohydrates and lower the effective blood sugar rise?

Ingestion of protein and of fat (especially monounsaturated fat) along with carb-rich foods often does indeed blunt the post-meal rise in blood glucose, effectively lowering the glycemic index of the meal. This appears to reflect increased production of certain hormones, … More scientific detail

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When I eat carbohydrates to excess in a day and develop higher insulin and glucose levels, does this produce a short-term increase in weight — and what is the nature and permanence of this weight gain?

If you gain a couple of pounds because of a day of indulgence, it’s not primarily fat weight you have gained, but rather water weight. Increases in blood insulin levels act on the kidneys to boost the retention of sodium … More scientific detail

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Is this a brittle diet that I must follow carefully; what harm will result if, for example, I drop off the diet for a weekend or a week?

Aside from a trivial weight gain if you “fall off the wagon” for a number of consecutive days, there should be no meaningful long-term adverse consequences to your weight or your health from occasional short-term lapses. In fact, even if … More scientific detail

Posted in CC Diets, FAQs | Comments Off on Is this a brittle diet that I must follow carefully; what harm will result if, for example, I drop off the diet for a weekend or a week?

Besides a Carb Concentrated Diet, what else do you recommend if it is not contraindicated by your condition or contradicted by your doctor?

A baby aspirin a day; medium chain triglycerides, supplements (discussed below), stress reduction and low salt.

Posted in CC Diets, FAQs | Comments Off on Besides a Carb Concentrated Diet, what else do you recommend if it is not contraindicated by your condition or contradicted by your doctor?

Why haven’t I heard more about Carb Concentration diets?

This formulation has just begun to be circulated. But millions of people bought the Hellers’ books, so a lot of people have heard about a special case of them. Unfortunately, the Hellers have never published their clinical experience in formal … More scientific detail

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I’m a vegetarian because I love animals and I’m worried about global warming. Could a CC diet work for me?

Sure, because a CC diet does not need to be a low-carb diet. You can eat all your favorite foods in your major daily meal. For your subsidiary meal, you can have low-carb plant foods like green salads, nuts, and … More scientific detail

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The Hellers say that eating carbs with three meals daily is bad for weight control. Then why did the Japanese stay so lean on their traditional diet that is about 80% carbs — mostly high-glycemic-index white rice?

If all your life your diet has been extremely low in fat, you’re not likely to ever get fat. That’s because almost all of the fatty acids in our bodies come from the fat in our diet. But that isn’t … More scientific detail

Posted in CC Diets, FAQs | Comments Off on The Hellers say that eating carbs with three meals daily is bad for weight control. Then why did the Japanese stay so lean on their traditional diet that is about 80% carbs — mostly high-glycemic-index white rice?

Just what is it about low insulin that is so protective?

Many things. Low insulin decreases the effective bioactivity of cancer-promotional hormones like IGF-I and estrogen by increasing the liver’s production of proteins that block their action. These hormones increase cancer risk by stimulating cell multiplication and thereby boosting the rate … More scientific detail

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Will you have enough energy to do effective exercise on a CC diet? I tried an Atkins diet once, but I just didn’t feel much like exercising when I was on it.

That’s not uncommon. Studies show that people on low-carb diets tend to be less motivated to do aerobic exercise, probably because their liver glycogen stores are very low. (When runners run out of glycogen, they “hit the wall”.) But a … More scientific detail

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How can you know that CC diets will increase healthspan?

Most important is the literature on caloric restriction and intermittent fasting. But the clinical experience of the Hellers is that overweight people tend to get a lot leaner on CC diets, and metabolic parameters associated with metabolic syndrome (blood pressure, … More scientific detail

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You say that the number of consecutive hours of low insulin is what might matter. But on alternate-day fasting regimens, insulin levels are low for up to 36 hours consecutively. In rodents, we know that this is long enough to get an extension in longevity. Why do you think that 20 hours of low insulin with a CC diet is long enough to get the same effect?

The main reason we are advocating a CC diet rather than an alternate day diet is that we judge it as much more feasible for large numbers of humans to maintain indefinitely. Moreover, we are emphasizing healthy aging rather than … More scientific detail

Posted in Caloric Restriction and Intermittent Fasting, FAQs | Comments Off on You say that the number of consecutive hours of low insulin is what might matter. But on alternate-day fasting regimens, insulin levels are low for up to 36 hours consecutively. In rodents, we know that this is long enough to get an extension in longevity. Why do you think that 20 hours of low insulin with a CC diet is long enough to get the same effect?

If a person eats three meals a day and no snacks, his insulin will be at or near fasting levels for about 18 hours a day. Why is a few less hours a day of elevated insulin with CC diets so important?

Two points here. It’s not just the total number of hours, but the number of consecutive hours of low insulin that may be the key factor. The physiological adaptations that protect animals that are calorically restricted probably don’t happen instantly … More scientific detail

Posted in CC Diets, FAQs | Comments Off on If a person eats three meals a day and no snacks, his insulin will be at or near fasting levels for about 18 hours a day. Why is a few less hours a day of elevated insulin with CC diets so important?

I’ve read that reduced IGF-I activity is the real reason why calorie-restricted diets increase longevity and prevent or postpone cancer. Yet you say little about IGF-I. Will a CC diet reduce IGF-I levels?

Not necessarily. But what is important is IGF-I bioactivity. Because CC diets keep insulin low most of the day, the liver makes more of a protein called IGFBP-1 that binds to the IGF-I in the blood and prevents it from … More scientific detail

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Are there supplements that you specially recommend for enhancing the effect of the CC diet or otherwise strengthening healthy aging?

Yes. We recommend consideration of the following supplements: Acetyl-l-Carnitine and Alpha Lipoic Acid which can be best purchased through www.Juvenon.com where a discussion of their health benefits can be found. COQ-10 of the newer form called ubiquinol (rather than ubiquinone); … More scientific detail

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In what way might a CC diet slow the aging process?

Low insulin levels, maintained by the CC diet, decreases the effective bioactivity of a hormone IGF-I that, in rodent studies has emerged as a key driver of the aging process.

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I am well along in age, is it too late for me to benefit from a CC diet?

No. Calorie restriction and maintenance of low insulin levels can have a rapid impact on inflammation, oxidative stress, pain perception, growth factor activities, and the process of autophagy which helps to keep the interiors of our cells in optimal working … More scientific detail

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Besides concentrating my carbs in a single daily meal, are there special food choices that will enhance the effects of the CC diet?

Try not to binge on carbohydrates in this main meal and to eat the carbs with a balanced meal. The foods you choose, besides carbs, and in the other meals, can be chosen to be low in glycemic index.

Posted in FAQs, Supplements and Special Foods | Comments Off on Besides concentrating my carbs in a single daily meal, are there special food choices that will enhance the effects of the CC diet?

How important is exercise in this dietary regime and how best should exercise be adjoined to this diet to maximize its effect?

Exercise while insulin is low is much more effective in cutting fat than exercise after a meal when insulin is higher. And, besides its effect on body weight, exercise training can have a direct insulin sensitizing effect on the muscles … More scientific detail

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Will Carb Concentrated Diets Help Me Reduce the Risk of Insulin Resistance Syndrome, a.k.a. metabolic syndrome, which includes the risk of heart attack, stroke, type 2 diabetes, heart failure, hypertension, fatty liver disease, many common types of cancer, and aging-related cognitive decline and dementia?

We believe it will. This syndrome is a type of “fat poisoning” and chronically elevated insulin levels. Maintaining leanness with this diet and keeping insulin levels low, as this diet does, should be important.

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Will Carb Concentrated Diets Help Me Reduce the Risk of, or Delay the Onset of, Neurological Diseases such as Alzheimer’s and Parkinsons?

Recent research on Caloric Restriction–and on the effects of Alternate-Day Fasting which is a related low-insulin diet–suggest that they produce neuroprotective benefits in rodents; better preservation of cognitive function against diseases like Alzheimers; less loss of functional capacity following stroke; … More scientific detail

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Concentrate Your Carbs!

Based on seven different pillars of human knowledge, described below, concentrating the consumption of high-glycemic carbohydrates in one of the daily meals, and thus maintaining low insulin levels for the rest of the day, appears to be the most promising … More scientific detail

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Neuroprotective Potential of Calorie Restriction, Alternate-Day Fasting, and Carb-Concentrated Diets

A considerable amount of recent research has focused on the neuroprotective properties of intermittent fasting and chronic calorie restriction; the impacts of calorie restriction and alternate-day fasting appear to be quite parallel in this regard, although the effects of alternate-day … More scientific detail

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Disclaimer

The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. … More scientific detail

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Healthy Aging Through Dietary Means

This evolving website is currently focused on ways and means of strengthening healthy aging through a class of diets called Carbohydrate Concentration (CC) diets. In these diets, the dieter concentrates his or her consumption of carbohydrates in one meal, eating … More scientific detail

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Professor Benjamin Treadwell’s Endorsement

I have read Jeremy Stone’s article “Concentrate Your Carbs!” proposing the widespread adoption of the concept of Carbohydrate-Concentration (CC) Diets in which dieters restrict their consumption of high-glycemic carbohydrates to a single daily meal while avoiding such foods in any … More scientific detail

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